| NOTES FROM THE SECOND ROUND |
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| POS | NAME | RND 1 | RND 2 | RND 3 | RND 4 | TOT |
| 1 | Emiliano Grillo | 66 | 63 | - | - | (-13) |
| T2 | Tom Hoge | 66 | 67 | - | - | (-9) |
| T2 | Tony Finau | 67 | 66 | - | - | (-9) |
| 4 | Russell Knox | 65 | 69 | - | - | (-8) |
THINGS TO KNOW
 |  | Emiliano Grillo ties his lowest round of his PGA TOUR career with 8-under 63 |
| | Emiliano Grillo extends his streak of par-or-better rounds at the Mayakoba Golf Classic presented by UNIFIN to a perfect 18-for-18 |
| | Tony Finau seeks second career PGA TOUR victory and first since the 2016 Puerto Rico Open |
| | Guadalajara native Carlos Ortiz sits T9 and seeks to win in back-to-back PGA TOUR starts |
| | Making his first PGA TOUR start as professional, 2019 U.S. Amateur champion Andy Ogletree is inside the top 10 |
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